Human PIGW activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PIGW
Locus ID	284098
Kit Components	GA117094G1, PIGW gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA117094G2, PIGW gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA117094G3, PIGW gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178517, NM_001346754, NM_001346755
Synonyms	Gwt1; HPMRS5
Summary	The protein encoded by this gene is an inositol acyltransferase that acylates the inositol ring of phosphatidylinositol. This occurs in the endoplasmic reticulum and is a step in the biosynthesis of glycosylphosphatidylinositol (GPI), which anchors many cell surface proteins to the membrane. Defects in this gene are a cause of the age-dependent epileptic encephalopathy West syndrome as well as a syndrome exhibiting hyperphosphatasia and cognitive disability (HPMRS5). [provided by RefSeq, Jul 2017]

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