Human Nephrocystin 4 (NPHP4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NPHP4
Locus ID	261734
Kit Components	GA116937G1, Nephrocystin 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116937G2, Nephrocystin 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116937G3, Nephrocystin 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291593, NM_001291594, NM_015102, NR_111987
Synonyms	POC10; SLSN4
Summary	This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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