Human DOS (CBARP) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CBARP
Locus ID	255057
Kit Components	GA116807G1, DOS gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116807G2, DOS gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116807G3, DOS gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_152769
Synonyms	BARP; C19orf26; DOS
Summary	Negatively regulates voltage-gated calcium channels by preventing the interaction between their alpha and beta subunits. Thereby, negatively regulates calcium channels activity at the plasma membrane and indirectly inhibits calcium-regulated exocytosis.[UniProtKB/Swiss-Prot Function]

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