Human Syntaxin binding protein 4 (STXBP4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	STXBP4
Locus ID	252983
Kit Components	GA116734G1, Syntaxin binding protein 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116734G2, Syntaxin binding protein 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116734G3, Syntaxin binding protein 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178509
Synonyms	Synip
Summary	Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity).[UniProtKB/Swiss-Prot Function]

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