Human ORAV1 (ORAOV1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LTO1
Locus ID	220064
Kit Components	GA116558G1, ORAV1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116558G2, ORAV1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116558G3, ORAV1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153451
Synonyms	TAOS1
Summary	The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery (PubMed:26182403). May be required for biogenesis of the large ribosomal subunit and initiation of translation (PubMed:23318452). May play a role in the regulation of proline metabolism and ROS production (PubMed:24930674).[UniProtKB/Swiss-Prot Function]

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