Human DHFRL1 (DHFR2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DHFR2
Locus ID	200895
Kit Components	GA116366G1, DHFRL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116366G2, DHFRL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116366G3, DHFRL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001195643, NM_176815
Synonyms	DHFRP4
Summary	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Binds its own mRNA and that of DHFR.[UniProtKB/Swiss-Prot Function]

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