Human C1orf86 (FAAP20) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FAAP20
Locus ID	199990
Kit Components	GA116327G1, C1orf86 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116327G2, C1orf86 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116327G3, C1orf86 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001146310, NM_001256945, NM_001256946, NM_001256947, NM_001282670, NM_001282671, NM_001282672, NM_001282673, NM_182533, NR_046424, NR_046425, NR_046426, NR_046427
Synonyms	C1orf86; FP7162
Summary	Component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. Promotes translesion synthesis via interaction with REV1.[UniProtKB/Swiss-Prot Function]

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