Human U2AF1L3 (U2AF1L4) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	U2AF1L4
Locus ID	199746
Kit Components	GA116316G1, U2AF1L3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116316G2, U2AF1L3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116316G3, U2AF1L3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040425, NM_144987, NR_110171, NR_110172, NR_110173, NR_163171, NR_163172, NR_163173, NM_001369824, NR_163169, NR_163170
Synonyms	U2AF1-RS3; U2AF1L3; U2AF1L3V1; U2AF1RS3; U2af26
Summary	RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity). Shows a preference for AGC or AGA (By similarity).[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.