Human GRAMD2A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	GRAMD2A
Locus ID	196996
Kit Components	GA116291G1, GRAMD2A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116291G2, GRAMD2A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116291G3, GRAMD2A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001012642
Synonyms	GRAM domain containing 2
Summary	Participates in the organization of endoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis. Constitutive tether that co-localize with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner. Pre-marks the subset of phosphtidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store operated calcium entry pathway (SOCE).[UniProtKB/Swiss-Prot Function]

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