Human PAOX activation kit by CRISPRa
CAT#: GA116286
PAOX CRISPRa kit - CRISPR gene activation of human polyamine oxidase
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PAOX |
Locus ID | 196743 |
Kit Components | GA116286G1, PAOX gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116286G2, PAOX gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116286G3, PAOX gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_152911, NM_207125, NM_207126, NM_207127, NM_207128, NM_207129, NR_109763, NR_109764, NR_109765, NR_109766 |
Synonyms | PAO |
Summary | Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion (PubMed:12477380). Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs (PubMed:12477380).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN407663 | PAOX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |