Human ANO6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ANO6
Locus ID	196527
Kit Components	GA116282G1, ANO6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116282G2, ANO6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116282G3, ANO6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001025356, NM_001142678, NM_001142679, NM_001142680, NM_001204803
Synonyms	BDPLT7; SCTS; TMEM16F
Summary	This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

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