Human RDHE2 (SDR16C5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SDR16C5
Locus ID	195814
Kit Components	GA116258G1, RDHE2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116258G2, RDHE2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116258G3, RDHE2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001318049, NM_001318050, NM_138969
Synonyms	RDH#2; RDH-E2; RDHE2
Summary	This gene encodes a member of the short-chain alcohol dehydrogenase/reductase superfamily of proteins and is involved in the oxidation of retinol to retinaldehyde. The encoded protein is associated with the endoplasmic reticulum and is predicted to contain three transmembrane helices, suggesting that it is an integral membrane protein. It recognizes all-trans-retinol and all-trans-retinaldehyde as substrates and exhibits a strong preference for NAD(+)/NADH as cofactors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

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