Human XAGE3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	XAGE3
Locus ID	170626
Kit Components	GA116216G1, XAGE3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116216G2, XAGE3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116216G3, XAGE3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_130776, NM_133179
Synonyms	CT12.3a; CT12.3b; GAGED4; PLAC6; pp9012; XAGE-3
Summary	This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is expressed in placenta and fetal liver/spleen, and may function in inhibiting cancer cell growth. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of this gene generates 2 transcript variants differing in the 5' UTR. [provided by RefSeq, Jul 2008]

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