Human SPTSSB activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPTSSB
Locus ID	165679
Kit Components	GA116131G1, SPTSSB gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116131G2, SPTSSB gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116131G3, SPTSSB gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040100, NM_001320679, NM_145035
Synonyms	ADMP; C3orf57; SSSPTB
Summary	Serine palmitoyltransferase (SPT; EC 2.3.1.50) catalyzes the first committed and rate-limiting step in sphingolipid biosynthesis. SSSPTB is a small SPT subunit that stimulates SPT activity and confers acyl-CoA preference to the SPT catalytic heterodimer of SPTLC1 (MIM 605712) and either SPTLC2 (MIM 605713) or SPTLC3 (MIM 611120) (Han et al., 2009 [PubMed 19416851]).[supplied by OMIM, Nov 2010]

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