Human TOR1AIP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TOR1AIP2
Locus ID	163590
Kit Components	GA116092G1, TOR1AIP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116092G2, TOR1AIP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116092G3, TOR1AIP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199260, NM_022347, NM_145034, NM_001349931, NM_001349933, NM_001349934, NM_001349935, NM_001349936, NM_001349937
Synonyms	IFRG15; LULL1; NET9
Summary	One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined. [provided by RefSeq, Mar 2017]

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