Human SPRED1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SPRED1
Locus ID	161742
Kit Components	GA116031G1, SPRED1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA116031G2, SPRED1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA116031G3, SPRED1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_152594
Synonyms	hSpred1; NFLS; PPP1R147; spred-1
Summary	The protein encoded by this gene is a member of the Sprouty family of proteins and is phosphorylated by tyrosine kinase in response to several growth factors. The encoded protein can act as a homodimer or as a heterodimer with SPRED2 to regulate activation of the MAP kinase cascade. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS). [provided by RefSeq, Jul 2008]

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