Human CLEC12A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CLEC12A
Locus ID	160364
Kit Components	GA115999G1, CLEC12A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115999G2, CLEC12A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115999G3, CLEC12A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001207010, NM_001300730, NM_138337, NM_201623, NM_201625
Synonyms	CD371; CLL-1; CLL1; DCAL-2; MICL
Summary	This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]

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