Human PAQR3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PAQR3
Locus ID	152559
Kit Components	GA115838G1, PAQR3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115838G2, PAQR3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115838G3, PAQR3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001040202, NM_177453, NM_001350105, NM_001350106, NR_146462, NR_146463, NR_146464, NR_146465
Synonyms	RKTG
Summary	This gene encodes a seven-transmembrane protein localized in the Golgi apparatus in mammalian cells. The encoded protein belongs to the progestin and adipoQ receptor (PAQR) family. This protein functions as a tumor suppressor by inhibiting the Raf/MEK/ERK signaling cascade. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2017]

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