Human Cklfsf8 (CMTM8) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CMTM8
Locus ID	152189
Kit Components	GA115827G1, Cklfsf8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115827G2, Cklfsf8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115827G3, Cklfsf8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001320308, NM_178868
Synonyms	CKLFSF8; CKLFSF8-V2
Summary	This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]

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