Human SLFN13 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SLFN13
Locus ID	146857
Kit Components	GA115586G1, SLFN13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115586G2, SLFN13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115586G3, SLFN13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_144682
Synonyms	SLFN10
Summary	Endoribonuclease that cleaves tRNAs and rRNAs (PubMed:29563550). Cleaves tRNAs 11 nucleotides from the 3'-terminus at the acceptor stem (PubMed:29563550). Does not act on tRNA(Sec) (PubMed:29563550). Able to restrict HIV-1 virus replication; ability to inhibit HIV-1 replication is dependent on endoribonuclease activity (PubMed:29563550).[UniProtKB/Swiss-Prot Function]

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