Human RLTPR (CARMIL2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CARMIL2
Locus ID	146206
Kit Components	GA115548G1, RLTPR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115548G2, RLTPR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115548G3, RLTPR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001013838, NM_001317026
Synonyms	CARMIL2b; LRRC16C; RLTPR
Summary	This gene encodes a member of the CARMIL (capping protein, Arp2/3, myosin-I linker) family of proteins. The encoded protein interacts with and negatively regulates the heterodimeric capping protein and promotes cell migration. Reduced expression of this gene has been observed in human psoriasis patients. Mutations in this gene cause a human immunodeficiency syndrome characterized by smooth muscle tumors and impaired T-cell function. [provided by RefSeq, May 2017]

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