Human RDH12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RDH12
Locus ID	145226
Kit Components	GA115512G1, RDH12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115512G2, RDH12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115512G3, RDH12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_152443
Synonyms	LCA13; RP53; SDR7C2
Summary	The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 13 and Retinitis Pigmentosa 53. [provided by RefSeq, Sep 2015]

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