Human POGLUT3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POGLUT3
Locus ID	143888
Kit Components	GA115474G1, POGLUT3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115474G2, POGLUT3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115474G3, POGLUT3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153705, NM_001363503, NM_001363502
Synonyms	MGC33424
Summary	Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C (PubMed:30127001). Can also catalyze the transfer of xylose from UDP-xylose but less efficiently (PubMed:30127001). Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3 (PubMed:30127001). May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway (PubMed:30127001).[UniProtKB/Swiss-Prot Function]

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