Human NCE2 (UBE2F) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UBE2F
Locus ID	140739
Kit Components	GA115405G1, NCE2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115405G2, NCE2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115405G3, NCE2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001278305, NM_001278306, NM_001278307, NM_001278308, NM_080678, NR_103498, NR_103499, NR_103500
Synonyms	NCE2
Summary	Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.[UniProtKB/Swiss-Prot Function]

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