Human UPRT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UPRT
Locus ID	139596
Kit Components	GA115344G1, UPRT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115344G2, UPRT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115344G3, UPRT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001307944, NM_145052, NR_030774, NM_001363821
Synonyms	FUR1; UPP
Summary	This gene encodes uracil phosphoribosyltransferase, which catalyzes the conversion of uracil and 5-phosphoribosyl-1-R-diphosphate to uridine monophosphate (UMP). This reaction is an important part of nucleotide metabolism, specifically the pyrimidine salvage pathway. The enzyme localizes to the nucleus and cytoplasm. The protein is a potential target for rational design of drugs to treat parasitic infections and cancer. [provided by RefSeq, Nov 2009]

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