Human DNAJC21 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DNAJC21
Locus ID	134218
Kit Components	GA115218G1, DNAJC21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA115218G2, DNAJC21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA115218G3, DNAJC21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001012339, NM_194283, NM_001348420
Synonyms	BMFS3; DNAJA5; GS3; JJJ1
Summary	This gene encodes a member of the DNAJ heat shock protein 40 family of proteins that is characterized by two N-terminal tetratricopeptide repeat domains and a C-terminal DNAJ domain. This protein binds the precursor 45S ribosomal RNA and may be involved in early nuclear ribosomal RNA biogenesis and maturation of the 60S ribosomal subunit. Mutations in this gene result in Bone marrow failure syndrome 3. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2017]

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