Human OSCAR activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OSCAR
Locus ID	126014
Kit Components	GA114909G1, OSCAR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114909G2, OSCAR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114909G3, OSCAR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001282349, NM_001282350, NM_130771, NM_133168, NM_133169, NM_206817, NM_206818
Synonyms	PIgR-3; PIGR3
Summary	Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]

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