Human QIL1 (C19orf70) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MICOS13
Locus ID	125988
Kit Components	GA114905G1, QIL1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114905G2, QIL1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114905G3, QIL1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308240, NM_205767, NM_001365761
Synonyms	MIC13; P117; QIL1
Summary	Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Constituent of mature MICOS complex, it is required for the formation of cristae junction (CJ) and maintenance of cristae morphology. Required for the incorporation of MICOS10/MIC10 into the MICOS complex.[UniProtKB/Swiss-Prot Function]

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