Human HEXIM2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HEXIM2
Locus ID	124790
Kit Components	GA114860G1, HEXIM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114860G2, HEXIM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114860G3, HEXIM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001303436, NM_001303437, NM_001303438, NM_001303439, NM_001303440, NM_001303441, NM_001303442, NM_001303443, NM_001303444, NM_144608
Synonyms	L3
Summary	This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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