Human DCUN1D3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	DCUN1D3
Locus ID	123879
Kit Components	GA114822G1, DCUN1D3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114822G2, DCUN1D3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114822G3, DCUN1D3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_173475
Synonyms	44M2.4; SCCRO3
Summary	Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane (PubMed:25349211). When overexpressed in transformed cells, may promote mesenchymal to epithelial-like changes and inhibit colony formation in soft agar (PubMed:25349211).[UniProtKB/Swiss-Prot Function]

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