Human TTC8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TTC8
Locus ID	123016
Kit Components	GA114796G1, TTC8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114796G2, TTC8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114796G3, TTC8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001288781, NM_001288782, NM_001288783, NM_144596, NM_198309, NM_198310, NM_001366535, NM_001366536, NR_159362
Synonyms	BBS8; RP51
Summary	This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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