Human ABH2 (ALKBH2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ALKBH2
Locus ID	121642
Kit Components	GA114759G1, ABH2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114759G2, ABH2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114759G3, ABH2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001001655, NM_001145374, NM_001145375, NM_001205179, NM_001205180, NR_026930, NR_026931
Synonyms	ABH2
Summary	The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]

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