Human LYPD1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LYPD1
Locus ID	116372
Kit Components	GA114588G1, LYPD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114588G2, LYPD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114588G3, LYPD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001077427, NM_001321234, NM_001321235, NM_144586
Synonyms	LYPDC1; PHTS
Summary	Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro increases receptor desensitization and decreases affinity for ACh of alpha-4:beta-2-containing nAChRs. May play a role in the intracellular trafficking of alpha-4:beta-2 and alpha-7-containing nAChRs and may inhibit their expression at the cell surface. May be involved in the control of anxiety.[UniProtKB/Swiss-Prot Function]

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