Human TLCD1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TLCD1
Locus ID	116238
Kit Components	GA114580G1, TLCD1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114580G2, TLCD1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114580G3, TLCD1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160407, NM_138463
Synonyms	TLC domain containing 1
Summary	Regulates the composition and fluidity of the plasma membrane (PubMed:30509349). Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (PubMed:30509349). Does not appear to have any effect on LCPUFA synthesis (PubMed:30509349).[UniProtKB/Swiss-Prot Function]

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