Human LRP15 (LRRC3B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LRRC3B
Locus ID	116135
Kit Components	GA114566G1, LRP15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114566G2, LRP15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114566G3, LRP15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317808, NM_001317809, NM_001317810, NM_001317811, NM_052953
Synonyms	LRP15
Summary	The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]

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