Human NT5C3L (NT5C3B) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NT5C3B
Locus ID	115024
Kit Components	GA114506G1, NT5C3L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114506G2, NT5C3L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114506G3, NT5C3L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_052935, NR_033464, NR_033465
Synonyms	cN-IIIB; NT5C3L
Summary	Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).[UniProtKB/Swiss-Prot Function]

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