Human ORP8 (OSBPL8) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OSBPL8
Locus ID	114882
Kit Components	GA114482G1, ORP8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114482G2, ORP8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114482G3, ORP8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001003712, NM_001319652, NM_001319653, NM_001319655, NM_020841
Synonyms	MST120; MSTP120; ORP8; OSBP10
Summary	This gene encodes a member of a family of proteins containing an N-terminal pleckstrin homology domain and a highly conserved C-terminal oxysterol-binding protein-like sterol-binding domain. It binds mutliple lipid-containing molecules, including phosphatidylserine, phosphatidylinositol 4-phosphate (PI4P) and oxysterol, and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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