Human Nac1 (NACC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NACC1
Locus ID	112939
Kit Components	GA114379G1, Nac1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114379G2, Nac1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114379G3, Nac1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_052876
Synonyms	BEND8; BTBD14B; BTBD30; NAC-1; NAC1
Summary	This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Feb 2012]

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