Human MYL12B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MYL12B
Locus ID	103910
Kit Components	GA114349G1, MYL12B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114349G2, MYL12B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114349G3, MYL12B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001144944, NM_001144945, NM_001144946, NM_033546
Synonyms	MLC-B; MRLC2
Summary	The activity of nonmuscle myosin II (see MYH9; MIM 160775) is regulated by phosphorylation of a regulatory light chain, such as MRLC2. This phosphorylation results in higher MgATPase activity and the assembly of myosin II filaments (Iwasaki et al., 2001 [PubMed 11942626]).[supplied by OMIM, Mar 2008]

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