Human TIMM50 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TIMM50
Locus ID	92609
Kit Components	GA114227G1, TIMM50 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114227G2, TIMM50 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114227G3, TIMM50 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001001563, NM_001329559
Synonyms	TIM50; TIM50L
Summary	This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis. [provided by RefSeq, Jul 2016]

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