Human MYLK3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MYLK3
Locus ID	91807
Kit Components	GA114157G1, MYLK3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114157G2, MYLK3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114157G3, MYLK3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001308301, NM_182493
Synonyms	caMLCK; MLCK; MLCK2
Summary	Phosphorylation of cardiac myosin heavy chains (see MYH7B, MIM 609928) and light chains (see MYL2, MIM 160781) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes (Chan et al., 2008 [PubMed 18202317]).[supplied by OMIM, Jul 2008]

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