Human CHMP7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CHMP7
Locus ID	91782
Kit Components	GA114155G1, CHMP7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114155G2, CHMP7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114155G3, CHMP7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001317899, NM_152272, NM_001363183
Summary	ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase (PubMed:26040712). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase (PubMed:26040712). Plays a role in the endosomal sorting pathway (PubMed:16856878).[UniProtKB/Swiss-Prot Function]

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