Human Protein kinase like protein SgK493 (PKDCC) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PKDCC
Locus ID	91461
Kit Components	GA114118G1, Protein kinase like protein SgK493 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114118G2, Protein kinase like protein SgK493 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114118G3, Protein kinase like protein SgK493 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_138370
Synonyms	SGK493; Vlk
Summary	Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29 (PubMed:25171405). Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation (PubMed:25171405). May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane (By similarity).[UniProtKB/Swiss-Prot Function]

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