Human ATPBD3 (CTU1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CTU1
Locus ID	90353
Kit Components	GA114008G1, ATPBD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA114008G2, ATPBD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA114008G3, ATPBD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145232
Synonyms	ATPBD3; NCS6
Summary	Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.[UniProtKB/Swiss-Prot Function]

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