Human C9orf140 (SAPCD2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SAPCD2
Locus ID	89958
Kit Components	GA113965G1, C9orf140 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113965G2, C9orf140 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113965G3, C9orf140 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178448
Synonyms	C9orf140; p42.3
Summary	Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (By similarity). Negatively regulates the mitotic apical cortex localization of GPSM2 (PubMed:26766442). Involved also in positive regulation of cell proliferation and tumor cell growth (PubMed:23576022, PubMed:23704824).[UniProtKB/Swiss-Prot Function]

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