Human ARHGAP11B activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGAP11B
Locus ID	89839
Kit Components	GA113937G1, ARHGAP11B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113937G2, ARHGAP11B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113937G3, ARHGAP11B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039841, NR_148423
Synonyms	B'-T; B -T; FAM7B1
Summary	Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex (PubMed:25721503). Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis (PubMed:25721503). Does not possess GTPase activator activity (PubMed:25721503).[UniProtKB/Swiss-Prot Function]

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