Human UNK unkempt (UNK) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	UNK
Locus ID	85451
Kit Components	GA113891G1, UNK unkempt gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113891G2, UNK unkempt gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113891G3, UNK unkempt gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080419, NR_038131
Synonyms	UNKEMPT; ZC3H5; ZC3HDC5
Summary	Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280).[UniProtKB/Swiss-Prot Function]

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