Human FRMD5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	FRMD5
Locus ID	84978
Kit Components	GA113814G1, FRMD5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113814G2, FRMD5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113814G3, FRMD5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001031729, NM_001286490, NM_001286491, NM_001322949, NM_001322950, NM_001322951, NM_032892, NR_104455
Synonyms	FERM domain containing 5; FLJ41022; MGC14161
Summary	May be involved in regulation of cell migration (PubMed:22846708, PubMed:25448675). May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation (PubMed:25448675).[UniProtKB/Swiss-Prot Function]

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