Human HSH2D activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	HSH2D
Locus ID	84941
Kit Components	GA113786G1, HSH2D gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113786G2, HSH2D gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113786G3, HSH2D gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291274, NM_032855, NR_111903, NR_111904, NM_001352265, NM_001352266, NM_001369808, NR_163150, NR_163152, NR_163153, NR_163155, NM_001369809, NR_163151, NR_163154, NR_163156
Synonyms	ALX; HSH2
Summary	T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these signaling pathways (Greene et al., 2003 [PubMed 12960172]).[supplied by OMIM, Mar 2008]

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