Human ORAI1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ORAI1
Locus ID	84876
Kit Components	GA113733G1, ORAI1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA113733G2, ORAI1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA113733G3, ORAI1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_032790
Synonyms	CRACM1; IMD9; ORAT1; TAM2; TMEM142A
Summary	The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1). [provided by RefSeq, Sep 2011]

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